Mereletinib For Advanced Non-small Cell Lung Cancer CAS 1421373-65-0

Basic Info

Model No.: 1421373-65-0

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

Mereletinib or Osimertinib (AZD-9291) CAS number is 1421373-65-0 which is a drug for the treatment of advanced non-small cell lung cancer, FDA expedited the approval process and approved the listing on 13th,November, 2015 . It is a kind of epidermal growth factor receptor (EGFR) kinase inhibitor, by inhibiting EGFR-T790M play a role in inhibiting tumor cell proliferation and promote apoptosis, clinical treatment for the transfer of epidermal growth factor receptor (EGFR) T790M positive mutation Non-small cell lung cancer. EGFR mutation is the most common genetic variants (50% -60%) in East Asian patients, including lung adenocarcinoma in China, and Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-tkis) can benefit about 70% of patients with mutations And 50% -60% of mutations in patients with EGFR-TKIs treatment failure due to T790M mutation, targeting the T790M mutation of the third generation of epidermal growth factor receptor tyrosine kinase inhibitor Mereletinib CAS number 1421373-65-0 will make nearly 30% of the EGFR mutation patient's survival time increased.

Thera. Category: Anti-Neoplastic

Cas No.: 1421373-65-0

Synonym:Osimertinib (AZD-9291);ZAD9291;AZD9291, Osimertinib;AZD9291 Base;Osimertinib Base;N-(2-{[2-(Dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin;AZD9291, >=98%;AZD9291 (free base);

Molecular Formula:C28H33N7O2

Molecular Weight: 499.61

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request

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