Intermediate of Fulvestrant 875573-67-4

Basic Info

Model No.: 875573-67-4

Additional Info

Packaging: AS REQUIRED

Productivity: G,KGS,

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Product Description

Fulvestrant intermediate 3 CAS 875573-67-4. Its preparation is usually using nandrolone as a raw material, get by acetylation reaction, NBS bromination reaction, LiBr / Li2CO3 elimination reaction, Grignard reagent addition reaction, etc. The key to the preparation process is the need to prepare thioether bromide C2F5 (CH2) 3S (CH2) 9Br in advance ,used for Grignard reagent addition reactions. There is a patent record another method, Use the same starting material of nandrolone, take Br (CH2) 8CH2OTBDMS Grignard reagent addition reaction, and then process the aromatization reaction and so on to get the Fulvestrant intermediate 3 CAS 875573-67-4.The number of steps in the preparation of the Fulvestrant intermediate 3 in this manner is five steps to complete,same as the previous method, but this method may be more costly.

Thera. Category:Anti-breast cancer

Cas No.:875573-67-4
Synonym :Fulvestrant interMediate N-2(1); Fulvestrant Intermediates--5-1(N-3-1);Estra-1,3,5(10)-triene-3,17-diol, 7-(9-bromononyl)-, (7α,17β)-;(7A,17BETA)-7-(9-BROMONONYL)ESTRA-1,3,5(10)-TRIENE-3,17-DIOL;(7α,17β)-7-(9-bromononyl)estra-1,3,5(10)-triene-3,17-diol
Molecular Formula:C27H41BrO2
 
Molecular Weight:477.52
Specifications:Available on request
Packing:Export worthy packing
Material Safety Data Sheet:Available on request
Usage: Intermediate of Fulvestrant
We are available for following Fulvestrant intermediate:
1) CAS 875573-63-0,(7alpha,17beta)-17-(Acetyloxy)-7-(9-bromononyl)estr-4-en-3-one
2) CAS 875573-66-3,(7a,17b)-7-(9-Bromononyl)-Estra- 1,3,5(10)-Triene-3,17-Diol 17-Acetate

3) CAS 875573-69-6),(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)Thio]Nonyl]-Estra-1,3,5(10)-Triene- 3,17-Diol 17-Acetate

4) Cas No.:153004-31-0, (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol

5) Cas 875573-67-4,(7a,17b)-7-(9-Bromononyl)estra-1,3,5(10)-triene-3,17-diol