FGF-401 CAS Number 1708971-55-4

Basic Info

Model No.: 1708971-55-4

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

FGF-401 CAS number 1708971-55-4, Molecular formula C25H30N8O4, Molecular weight 506.567, which is a FGFR4 inhibitor for the treatment of solid tumors. In Phase I clinical studies, FGF-401 was used as a FGFR4 inhibitor for the treatment of positive and negative hepatocellular carcinoma with positive FGFR4 and KLB expression. Phase I clinical studies have shown that FGF401 specifically targets FGFR4. FGF401 significantly improves selectivity to FGFR4 kinase domain and reduces adverse effects relative, compare to other same type of small molecule inhibitors. If the clinical data of Phase III is better,We believe it will be a hot product. At present we are also in the gram-level process validation stage. We kept it in a sealed glass bottle and refrigerated at minus 20 ° C. Now we has not done a detailed stability test. We recommend using within one month after opening the package, otherwise there may be some quality risk. Since this compound is newer, we can provide NMR, IR, liquid chromatographic and other information.

Thera. Category: Anti-Tumor

Cas No.: 1708971-55-4

Synonym:8-naphthyridine-1(2H)-carboxamide;0997;N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide

Molecular Formula:C25H30N8O4 

Molecular Weight: 506.567 

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request

 Relation Product: 

FGF-401 CAS number 1708971-55-4

4-Fluoro-5-iodo-pyridin-2-ylamine CAS 1708974-12-2

2-amino-4-fluoro-cyanopyridine CAS1708974-11-1

6-bromo-7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine;FGF-401 Intermediate 4 CAS number 1708974-02-0

2-(dimethoxymethyl)-5,6,7,8-tetrahydro-1,8-naphthyridine-3-carbaldehyde;FGF-401 Intermediate 5 CAS number1708974-56-4