Ebastine Intermediate 6 Used for Allergic Diseases CAS 65214-84-8

Basic Info

Model No.: 65214-84-8

Additional Info

Packaging: As Quantity

Productivity: As Order

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: IN STOCK

Product Description

Ebastine intermediate 6 CAS number is 65214-84-8, some people also called Ebastine N-2, it has two common methods, one is use cheap  y-butyrolactone as the starting material, after acylation, Friedel Crafts reaction ans so on, through 6 steps reaction to get target compounds Ebastine intermediate 6. All route line is mild reaction conditions,without special equipment,each step reaction yield is high. The other is use Chlorodiphenylmethane and Ethyl 4-hydroxypiperidine-1-carboxylate as raw material, the target compound obtained by two step reaction, because N element of Chlorodiphenylmethane is active, in the first step must to protect N, so it increases the reaction steps and increased cost in certain. The difference between the two methods: the first method is the N element as an attack group, and the second method is the oxygen as   nucleophile agent. During the reactions of oxygen In the process, N elements must be protected with protective groups. The differences between the two methods are not very large in principle, and they are relatively easy to be carried out in organic synthesis

Thera. Category: Anti-allergic  

Cas No.: 65214-84-8

Synonyms:  ethyl 4-diphenylmethoxy-1-piperinecarboxylate; 1-Piperidinecarboxylic acid,4-(diphenylmethoxy)-,ethyl ester;ethyl 4-(diphenylmethoxy)-1-piperidinecarboxylate; 4-(diphenylmethoxy)-1-(ethoxycarbonyl)piperidine; 1-ethoxycarbonyl-4-diphenylmethoxypiperidine;

MF:C21H25NO3

NW:339.42800

Assay: ≥99%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage: Used to treat the allergic rhinitis