2-Amino-4-Chlorobenzoic Acid CAS 89-77-0

Basic Info

Model No.: 89-77-0

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Port: Beijing,Shanghai,Shenzhen

Product Description

    2-Amino-4-chlorobenzoic acid CAS 89-77-0, the appearance of a white crystalline powder, can be used as a pesticide, pharmaceutical intermediates. In the pharmaceutical intermediates, it is mainly used in the synthesis of tianeptine and afatinib intermediates. The application process of synthesis of afatinib intermediate is as following: at room temperature, 100g of 2-amino-4-chlorobenzoic acid was added to a 500ml round bottom four-neck reaction flask, 300ml of acetic anhydride was added, vigorously stirred, reflux reaction, Thin layer chromatography (TLC) monitoring, reaction for 5 hours; after the reaction is completed, the reaction solution is poured into ice water, a large amount of white solid is precipitated, washed with water, and filtered with suction to obtain 117 g of 2-acetylamino-4-chlorobenzoic acid. It can used directly in the next reaction without Purification..

Cas No.:89-77-0

Synonyms:3-AMINO-4-CARBOXY-1-CHLOROBENZENE;2-AMINO-4-CHLOROBENZOIC ACID;2-CARBOXY-5-CHLOROANILINE;2,4-ACBA;4-chloroanthranil acid;p-Chloro-o-Amino Benzoic Acid;4-ChloroanthranilicAcid98%;4-CHLORO-2-AMINOBENZOIC ACID;
 

Molecular Formula: C7H6ClNO2

Molecular Weight:171.58

Purity: ≥98%

Packing: Export worthy packing

Material Safety Data Sheet: Available on request