Home > Active Pharmaceutical Ingredients > Top Purity Entecavir hydrate 209216-23-9

Top Purity Entecavir hydrate 209216-23-9

Unit Price:

USD 47.0000 - 65.0000 / Gram

Payment Type:

L/C,T/T

Incoterm:

CIF

Min. Order:

1 Gram

Delivery Time:

7 Days

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Basic Info

Model No.: 209216-23-9

Function: Disinfectant and Preservatives

Grade Standard: Medicine Grade

State: Solid

Additional Info

Packaging: Export worthy packing

Productivity: 50KG/Y

Brand: VOLSENCHEM

Transportation: Air,DHL FEDEX EMS

Place of Origin: CHINA

Supply Ability: Immediately

Certificate: DMF OPEN PART

Product Description

Entecavir hydrate 209216-23-9

Entecavir hydrate(209216-23-9) is a nucleoside analog(more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process.

Thera. Category: Adult chronic hepatitis B

Cas No.: 209216-23-9

Synonym:entecavir hydrate;ENTECAVIR MONOHYDRATE;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;Entecavir hydrate / 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate

Molecular Formula: C12H17N5O4

Molecular Weight:295.29448

Pharmacopeia: In house Spec.

Specifications:Available on request

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage:This product is applicable to the treatment of adult chronic hepatitis B.

CERTIFICATE OF ANALYSIS

Product Name	Entecavir Monohydrate	Cas No.	209216-23-9
Producing Date	2014-10-03	Batch No.	20141003
Assaying Date	2014-10-03	Reporting Date	2014-10-03
Expiry Date	2016-10	Quantity	50Gram

Items		Specifications	Results
Appearance		White or off-white powder	White powder
Identification		1)The IR absorption specturm of the sample must be same with entecavir 2) RT of the sample should match that of standard assay preparation	Comform
Water		5.8%~6.5%	6.1%
Optical rotation		+24°~+28° (DMF:MOH=1:1 C=1%)	+27.2°
Residue on ignition		≤0.10%	0.07%
Heavy Metals		≤20ppm	Conforms
Related substances	Total impurities	≤0.30%	0.07%
Related substances	Single impurity	≤ 0.1%	0.03%
Residual solvents	dichloromethane	≤600ppm	100PPM
	methanol	≤1000ppm	300PPM
	tetrahydrofuran	≤700ppm	ND
	toluene	≤600ppm	ND
Assay (HPLC)		99.8% ~102.0%(On anhydrous basis)	≥99.9%
Particle size		D90≤30um	Conform
Conclusion: The product corresponds to the requirements of in house standard.

Related intermediates:

1)2-Amino-6-Benzyloxypurine 19916-73-5

2)(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane 110567-22-1

3)(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol 142217-77-4

4)(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol 142217-78-5

5)2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one CAS 142217-81-0

HBV Inhibitor Entecavir 209216 23 9 Low Price 99% Purity White Power Entecavir Monohydrate Entecavir Hydrate

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