Polypeptide Antibiotic Polymyxin B Sulfate 1405-20-5

Basic Info

Model No.: 1405-20-5

Additional Info

Productivity: Customized

Brand: VOLSENCHEM

Transportation: Ocean,Air

Place of Origin: CHINA

Supply Ability: COMMERCIAL

Product Description

Polymyxin B sulfate CAS number 1405-20-5 is a kind of basic peptide antibiotic which is produced by polymyxes and composed of many kinds of amino acids and fatty acids. It is a multi-component product, including polymyxin B1, B2, B3, B1-1, where B1 and B2 are the active ingredients, B3 and B1-1 are the main impurities.Polymyxin B sulfate CAS 1405-20-5 almost have antibacterial effect on the Gram-negative bacteria, due to the high efficient on Pseudomonas aeruginosa, was the first choice for anti-Pseudomonas aeruginosa drugs, now is currently effective for the treatment of super bacteria, so it paid by much attention, but its impurities B3 and B1-1 have big toxic side effects, a serious impact on the clinical use of polymyxin B. At present, the main use is for external, but only for the local use of sensitive bacteria in the eyes, ears, skin, mucosal infection and burn infection of Pseudomonas aeruginosa. At present, the production of polymyxin B sulfate CAS number 1405-20-5 is mainly biosynthesis by microbial fermentation, and then refined and purified, the impurity B3 is about 3.5% and the impurity B1-1 is 7.5%. if further achieve to oral or injectable drug requirements, it must be innovative technology to further reduce the B3 and B1-1 these two impurities.

Thera. Category: Anti-Biotics

Cas No.: 1405-20-5

Synonym:POLYMYXIN B SULFATE;POLYMYXIN B SULFATE, BACILLUS POLYMYXA;POLYMYXIN B SULFATE SALT;POLYMYXIN B SULPHATE;POLYMYXIN B (PMB);POLYMIXIN B SULFATE;POLYMYXIN B;POLYMYXIN-B 2,5-SULFATE;

Molecular Formula: C56H100N16O17S

Molecular Weight: 1301.56

Pharmacopeia: in house spe.

Specifications:Available on request

Packing:Export worthy packing

Material Safety Data Sheet:Available on request