Nintedanib OR BIBF 1120 CAS number 656247-17-5

Basic Info

Model No.: 656247-17-5

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Ocean,Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Product Description

Nintedanib is referred to as BIBF 1120 CAS number is 656247-17-5, molecular weight is C31H33N5O4 molecular formula is 539.62482. Nintedanib is an oral administration of triple tyrosine kinase inhibitors, targets include platelet-derived growth factor (PDGF), vascular endothelium Growth factor (VEGF) and basic fibroblast growth factor (bFGF), but also inhibit MAPK and Akt activation. At present, mainly for cancer treatment, such as colorectal cancer, ovarian cancer, multiple myeloma. Nintedanib's application for marketing authorization for Idiopathic Pulmonary Fibrosis (IPF) in 2014 was confirmed by the European Medicines Agency (EMA) and included in the accelerated approval list by the EMA.

Thera. Category: A Potent Kinase Inhibitor

Cas No.: 656247-17-5

Synonym:Nintedanib (BIBF 1120);Nintedanib/Intedanib/Vargatef;Intedanib Vargatef;methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate Nintedanib (BIBF 1120);Vargatef (nintedanib); Intedanib;Vargatef;Nintedanib;

Molecular Formula: C31H33N5O4

Molecular Weight: 539.62482

Purity: ≥98.%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

BIBF1120 (Vargatef)  is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors.