LY2835219 Intermediate 5 CAS Number 1231930-33-8

Basic Info

Model No.: 1231930-33-8

Additional Info

Packaging: 1KGS/DRUM

Productivity: Commercial scale

Brand: VOLSENCHEM

Place of Origin: CHINA

Product Description

LY2835219 Intermediate 5 CAS number 1231930-33-8, Molecular formula C11H12BrFN2, Molecular weight 271. Its brief synthetic method is as follows, use Propan-2-amine as raw material, followed by adding acetyl chloride, ethyl acetate, potassium carbonate,Through reaction to get the first step product N-isopropyl acetamide, adding 4-bromo-2,6-difluoroaniline, in the chlorination form of phosphorus oxychloride and acid binding agent triethylamine under the action of amidine reaction to form acetamidine compounds, the compounds under the action of potassium tert-butoxide and N-methyl formamide,take substitution ring reaction to produce the target product LY2835219 intermediates 5. This is the synthetic route of patent. the use of synthetic ideas is the functional group gradual increase in the way, so the reaction steps is more. We believe that the chemical synthesis of the master who can see the existence of the problems and defects. we do not do too much comment. We have successfully carried out commercial production, the first order of the quantity is 20kg which has been delivered to customers and acceptance by them.

Thera. Category: Anti -cancer

Cas No.:1231930-33-8

Synonym:LY2835219 Intermediate ;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole;6-Bromo-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole;1H-BenziMidazole, 6-broMo-4-fluoro-2-Methyl-1-(1-Methylethyl)-

Molecular Formula:C11H12BrFN2

Molecular Weight: 271

Pharmacopeia: In house Spec.

Specifications:Available on request

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Related Intermediates : 

1-[(6-bromo-3-pyridinyl) methyl] -4-ethylPiperazine,cas 1231930-25-8

6-bromo-1-isopropyl-2-methyl-1H-benzo [d] imidazole CAS number 1038408-36-4

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole cas 1231930-33-8

CAS 1231930-37-2,1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-