Linezolid N-3,CAS Number 174649-09-3

Basic Info

Model No.: 174649-09-3

Additional Info

Productivity: Customized

Brand: VOLSENCHEM

Transportation: Ocean,Air

Place of Origin: CHINA

Supply Ability: COMMERCIAL

Product Description

The third step of linezolid also known as linezolid N-3, the CAS number is 174649-09-3, molecular formula C15H19FN2O6S, the appearance of white to pale yellow powder, It is the most demand for linezolide intermediates CAS number 74649-09-3, Most of the relevant needs of customers will purchase this intermediate. For his synthesis, we think there are two kinds of feasible ideas. The first idea is take 3,4 - difluoronitrobenzene and morpholine in alkaline conditions under the substitution reaction to get 3 - fluoro - 4 - morpholino - nitrobenzene, and then with ferric chloride and activated carbon,take the reaction to get 3-fluoro-4-morpholino aniline, and then through three step can be obtained linezolid N-3, the advantages of this reaction process is the separation and purification process is difficult. The second idea is take (S) - epichlorohydrin and maleimide reaction to produce the corresponding product after adding 3 - fluoro - 4 - morpholino - aniline to get the corresponding intermediates, and then after through three step reaction can be get Linezolid N-3 CAS number is 174649-09-3, this idea is simple, easy to purify the product, suitable for large-scale production. Linezolid N-3 is a very critical intermediate for linezolid, and we believe that the poor quality of this intermediate determines the  quality of linezolid. So we are very concerned about the quality of this intermediate indicators. At present we can make his chemical purity of more than 99%, isomer content control within 0.15%.

Thera. Category: Anti-fungal

Cas No.:  168828-82-8

Synonym:(R)-(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate;(5R)-3-[3-Fluoro-4-(4-Morpholinyl)phenyl]-5-[[(Methylsulfonyl)oxy]Methyl]-2-oxazolidinone;2-Oxazolidinone, 3-[3-fluoro-4-(4-Morpholinyl)phenyl]-5-[[(Methylsulfonyl)oxy]Methyl]-, (5R)-;Linezolid related Compound;Linezolid USP RC D;(R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate;(R)-[3-(3-Fluoro-4-Morpholinophenyl)-2-oxo-5-oxazolidinyl]Methyl Methanesulfonat;(R)-(3-(3-flouro-4-Morpholinophenyl)-2-oxo-5-oxazolidinyl)Methyl Methanesulfonate;

Molecular Formula: C15H19FN2O6S

Molecular Weight: 374.3845632

Pharmacopeia: in house spe.

Specifications:Available on request

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Related intermediate of Linezolid:

1) (5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2-oxazolidione CAS 168828-82-8

2) (R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate CAS 174649-09-3