GABA-like Drug Baclofen CAS Number 1134-47-0

Basic Info

Model No.: 1134-47-0

Function: Nervous System Drugs

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Port: Beijing,Shanghai,Shenzhen

Product Description

Baclofen CAS number is 1134-47-0, an analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), is mainly used for skeletal muscle relaxation, neurological disorders such as multiple sclerosis and trauma, etc. There are fewer side effects at the therapeutic level and have been widely used in patients with spinal cord injury since the 1970s. Currently available administration methods include oral administration of a common tablet, administration by spinal canal or lumbar puncture, or intrathecal administration by implantation.
Baclofen CAS number 134-47-0 was launched in Italy in 1973 and is the first clinically selective GABA beta receptor agonist with 10 mg and 25 mg tablets for the treatment of cerebrovascular accidents, cerebral palsy, meningitis, multiple Sclerosing disease, muscle spasm caused by spinal cord injury and head trauma. In 1992, baclofen tablets were marketed in the United States with specifications of 10 mg and 20 mg. Baclofen was clinically treated with cerebrovascular disease and stroke-induced hemiplegia, spinal cord injury, and multiple sclerosis. Get a good therapeutic effect. There are many other applications, such as treatment of central refractory hiccups and neuropathic pain, treatment of dysregulated urination, and urinary dysfunction after spinal cord injury. Treatment reduces dependence on addictive substances such as alcohol, tobacco,. Acid gastroesophageal reflux cough and so on.
At present, there are many other similar drugs on the market such as diazepam, dantrolene, and tetonidine. Diazepam has the effect of relieving phlegm, but there will be obvious sleepiness. The patient can only stay in bed and affect the quality of life of the patient. Dantrolene restricts the patient's ability to get up, and a small number of patients are prone to hepatitis after a long time. The side effects of tetonidine are also called obvious. Compared with it, baclofen showed obvious advantages: stable drug effect and less side effects.
Baclofen can also be used to improve the symptoms of hypertonia caused by pyramidal damage, spastic hemiplegia and paraplegia caused by different causes, such as children with cerebral palsy, tetanus, refractory hiccups; improvement of Duchenne muscular dystrophy Repeated vomiting in patients with duodenal obstruction; relieve trigeminal neuralgia, postherpetic neuralgia, improve muscle rigidity caused by extrapyramidal damage such as Parkinson's disease, tardive dyskinesia, and lightness of Huntington's chorea Degree improvement. Residual urine in patients with paraplegia is reduced after intravenous injection.

Cas No.:1134-47-0

Synonyms:4-Amino-3-(p-chlorophenyl)butyric acid;Benzenepropanoic acid, β-(aminomethyl)-4-chloro-;CIBA Ba 34647;DL-4-Amino-3-p-chlorophenylbutanoic acid;DL-Baclofen;Hydrocinnamic acid, 
 

Molecular Formula: C10H12ClNO2

Molecular Weight: 213.66

Purity: ≥98%

Packing: Export worthy packing

Material Safety Data Sheet: Available on request