Home > Contract Manufacturing > CAS 189188-57-6,Tegaserod Maleate

CAS 189188-57-6,Tegaserod Maleate

Unit Price:

USD 916.0000 - 950.0000 / Kilogram

Payment Type:

T/T

Incoterm:

CIF

Min. Order:

1 Kilogram

Delivery Time:

7 Days

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Basic Info

Model No.: 189188-57-6

Additional Info

Packaging: AS REQUIRED

Productivity: 20KGS/M

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: IN Stock

Certificate: GMP Environment

Product Description

We,ChinaTegaserod Maleate Suppliers and China 22795-99-9 Tegaserod Maleate Cas No.189188-57-6

Manufacturers with quality you can count on including those with CAS number189188-57-6, You can be assured that all Tegaserod Maleate 189188-57-6 offered by Volsen, meet or exceed the grade requirements or specifications for each individual product.

Thera. Category:Gastrointestinal Agents
Cas No.:189188-57-6
Synonym:(2E)-2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentylhydrazinecarboximidamide
Molecular Formula:C20H27N5O5

Molecular Weight:417.
Pharmacopeia: in house spe.
Specifications:Available on request
Packing:Export worthy packing
Material Safety Data Sheet:Available on request

Usage: 1.A gastroproeinetic use in the treatment of irritable bowel syndrome.
2.A selective serotonin 5HT4-receptor partial agonist

COA Specification of Tegaserod Maleate Cas No.189188-57-6

Items	Specifications	Results
Appearance	A White powder	Conform
Identification	HPLC IR	Conform
Solubility	Scarcely soluble in water, sparingly soluble in methanol, slightly soluble in ethanol and scarcely soluble in chloroform	Conform
Methanol	≤0.30%	Conform
Melting Point	188.0°C ~193.0°C	188.5°C~190.5°C
Loss on drying	≤0.50%	0.16%
Residual on ignition	≤0.10%	0.07%
Heavy Metals	≤10ppm	Conform
Residual solvent	Ethanol≤5000ppm Methanol≤3000ppm	Conform Conform
Related Substances(HPLC)	Single impurity≤0.3% Total impurities≤1.0%	0.08% 0.13%
Assay(based on drying)	≥99.0	99.3%
Particle size	50%≤70microns 90%≤205microns	Conform Conform
Conclusion: The product corresponds to the requirements of in house standard.
Storage Condition: Keep container tightly closed in a dry and well-venting place.

Tegaserod is a 5-HT4 agonist manufactured by Novartis and sold under the name Zelnorm for the management of irritable bowel syndrome and constipation.

Mechanism of action

The drug functions as a motility stimulant, achieving its desired therapeutic effects through activation of the 5-HT4 receptors of the enteric nervous system in the gastrointestinal tract. It also stimulates gastrointestinal motility and the peristaltic reflex, and allegedly reduces abdominal pain. Additionally, tegaserod is a 5-HT2B receptor antagonist.

CAS 189188 57 6 Tegaserod Maleate 189188 57 6 189188 57 6

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