Cas 127852-28-2,(R)-1-[3,5-Bis(trifluoromethyl) phenyl]ethanol[Intermediates of Aprepitant]

Basic Info

Model No.: 127852-28-2

Additional Info

Packaging: 1KGS/BAG

Productivity: 5KGS/M

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Product Description

Backed by a team of highly qualified and skilled professionals we are capable providers of high purity Aprepitant Intermediates (R)-1-[3,5-Bis(trifluoromethyl) phenyl]ethanol CAS 127852-28-2. Aprepitant Intermediates (R)-1-[3,5-Bis(trifluoromethyl) phenyl]ethanol CAS NO 127852-28-2 is high specification that use superior quality raw material ,and is strictly controlled by our experts. It is an main intermediate of Aprepitant, which is widely used in prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting. Furthermore, it also can apply to Major Depression. We can provide best service and fast shipment.

l Thera. Category: Anti- emetic

l Cas No.: 127852-28-2

l Synonym: R-MBT-PEL;(R)-BIS-3,5-TRIFLUOROMETHYL-1-PHENYLETHANOL;(R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL;(R)-1-[BIS-3,5-(TRIFLUOROMETHYL)PHENYL]ETHANOL;(1R)-1-[3,6-BIS(TRIFLUOROMETHYL)PHENYL]ETHANOL;(R)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHAN-1-OL;(R)-1-[3,5-BIS(TRIFLUORO-METHYL)-PHENYL]ETHANOL 98%;(1R)-(+)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol;

l Molecular Formula: C10H8F6O

l Molecular Weight: 258.16

l Assay:≥98%

l Packing: Export worthy packing

l Material Safety Data Sheet: Available on request

l Usage: Intermediate of Aprepitant

Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound .Aprepitant is manufactured by Merk&Co. under the brand name Emend for prevention of acute and delayed CINV) and for prevention of postoperative nausea and vomiting. It was approved by the FDA in 2003.

Aprepitant may also be useful in the treatment of cyclic vomiting syndrome & late-stage chemotherapy induced vomiting, but there are few studies to date.

On January 2008, the FDA approved fosaprepitant, an intravenous form of aprepitant, which is to be sold under the tradename Emend Injection in the US and as Ivemend in some other countries.