Bortezomib Intermediate (R)-BoroLeu-(+)-Pinanediol-CF3COOH 179324-87-9

Basic Info

Model No.: 179324-87-9

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Certificate: ISO

Product Description

(R)-BoroLeu-(+)-Pinanediol-CF3COOH 179324-87-9 is Bortezomib intermediate and Ixazomib, it has Molecular Formula: C15H28BNO2.C2HF3O2. Molecular Weight: 379.224.  Assay: 99%Package: 25g,100g,500g,1kg,10kg. (R)-BoroLeu-(+)-Pinanediol trifluoroacetate 179324-87-9 is used to make Ixazomib which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM).

Thera. Category: Anti cancer

Cas No.: 179324-87-9

Synonym: (1R)-(S)-PINANEDIOL 1-AMMONIUM TRIFLUOROACETATE-3-METHYLBUTANE-1-BORONATE;(R)-BoroLeu-(+)-Pinanediol-CF3COOH;(R)-BoroLeu-(+)-Pinanediol-CF3CO2H;(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate;(αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetate;Bortezomib Intermediate 1;Pinanedioltrifluoroacetate salt-;(R)-BoroLeu-(+)-Pinanediol trifluoroacetate

Molecular Formula:C15H28BNO2.C2HF3O2

Molecular Weight:379.224

Assay: ≥99.%

Packing: Export worthy packing

lMaterial Safety Data Sheet: Available on request 

Usage:

MLN9708 CAS 1201902-80-8 is a selective, potent, and reversible proteasome inhibitor.

Related intermediate:

1) 179324-87-9 (1R)-(S)-PINANEDIOL 1-AMMONIUM TRIFLUOROACETATE-3-METHYLBUTANE-1-BORONATE

2) 667403-46-5 CHEMBRDG-BB 7959525