Avanafil Intermediates 3 CAS Number 5909-24-0

Basic Info

Model No.: 5909-24-0

Function: Nervous System Drugs

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Product Description

Avanafil Intermediates 3 named as Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate CAS number is 5909-24-0,Molecular formula C8H9ClN2O2S, Molecular weight: 232.69. The synthesis route of Avanafil is longer, and the Avanafil Intermediates 3 is the relatively forward intermediate, and in many literatures it is directly used as the starting material for the first step, but in our synthesis system it is not the starting material, we use 2,4-dichloropyrimidine as a raw material by 3-step reaction to get Avanafil intermediate 3. The reaction in the first step to obtain 2,4-dichloropyrimidine-5-carboxylic acid, although the use of carbon dioxide into the carboxyl reaction,the conditions are very harsh, we have the ability to control the entire reaction process.

Cas No.: 5909-24-0

Synonyms:2-METHYLTHIO-4-CHLORO-5-ETHOXYCARBONYLPYRIMIDINE;4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester;ethyl 4-chloro-2-methylthio-5-pyrimidine-carboxyl;SIEHE AV22429;BUTTPARK 45\03-53;ETHYL 4-CHLORO-2-METHYLTHIO-5-PYRIMIDINECARBOXYLATE;ETHYL 4-CHLORO-2-METHYLTHIOPYRIMIDINE-5-CARBOXYLATE;ETHYL 4-CHLORO-2-(METHYLSULFANYL)-5-PYRIMIDINECARBOXYLATE;

Molecular Formula:C8H9ClN2O2S

Molecular Weight:232.69

Purity: ≥98%

Packing: Export worthy packing

Material Safety Data Sheet: Available on request

Related intermediate:

1) 41965-95-1,  3-CHLORO-4-METHOXYBENZYLAMINE HYDROCHLORIDE

2) 5909-24-0,Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

3)Avanafil CAS  330784-47-9

4)Avanafil intermediate 3 CAS number  330785-81-4

5) 2-aminomethylpyrimidine hydrochloride  CAS 372118-67-7,