An Immunosuppressive Agents Mizoribine Cas Number 50924-49-7

Basic Info

Model No.: 50924-49-7

Additional Info

Packaging: As required

Productivity: Commercial

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Certificate: Technical Support

Product Description

Mizoribine cas number 50924-49-7 is an antimetabolite that inhibits the purine synthesis pathway of nucleic acids, has immunosuppressive activity, and has almost no myelosuppressive effect and hepatotoxicity of azathioprine. The inhibition rate of mouse lgM antibody forming ability was 47.7%. In vitro experiments on various mammalian cultured cells Mizoribine cas 50924-49-7 can specifically inhibit lymphocyte proliferation. In an experiment in which rabbits are immunized with sheep red blood cells, the process of generating antibodies due to the primary response and the secondary response can be suppressed. In vitro experiments with dog and human peripheral blood lymphocytes can inhibit blast-like transformation reactions caused by various mitogenic factors. In the migration inhibition test of guinea pig macrophages, the migration of exudate cells in the peritoneal cavity can be attenuated. The thyroid transplantation, rat heart transplantation and dog kidney transplantation can prolong the implantation of the graft. Nucleic acid synthesis is inhibited by antagonizing the pathway from inosinic acid to guanylic acid in the synthesis of indole, but not in macromolecular nucleic acid (in vitro).

Thera. Category: Antimetabolite

Cas No.:50924-49-7

Synonyms: 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide;

NW: 259.25

M.W.:C9H13N3O6

Assay: ≥99%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request