5-Bromoisobenzofuran-1(3H)-one CAS 64169-34-2

Basic Info

Model No.: 64169-34-2

Additional Info

Packaging: As Quantity

Productivity: As Order

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: IN STOCK

Product Description

We are professional supplier of 5-Bromophthalide CAS 64169-34-2 that is an important intermediate for FG-4592. FG-4592 is a HIF α prolyl hydroxylase inhibitor that is approved for the treatment of anemia. 5-Bromophthalide CAS NO 64169-34-2 is white to pale yellow crystalline solid with the molecular formula of C8H5BrO2 and formula weight of 213.03. We have certain inventory. If you need 5-Bromophthalide 64169-34-2, please contact us.  

The production of 5-Bromophthalide cas 64169-34-2 is completed in three steps. The first step of bromination: adding phthalic anhydride and basic compound to water, after complete hydrolysis, slowly adding liquid bromine, stirring at high temperature, and post-treatment 5-bromophthalic acid; the second step of amination: using 5-bromophthalic acid as a solution, heating and refluxing to obtain 5-bromophthalic anhydride, and then without solvent The urea is melted and stirred at a high temperature to obtain 5-bromophthalimide; the third step is a reduction reaction: after ethanol and water are used as a solvent, the reducing agent is reduced, and then the acid is closed to obtain 5-Bromophthalide cas 64169-34-2.

Thera. Category: Anti-anemia.

Cas No.:64169-34-2

Synonyms: 5-BROMO-1(3H)-ISOBENZOFURANONE;5-BROMO-3H-ISOBENZOFURANONE;5-BROMO-2-BENZOFURAN-(3H)-ONE;5-BROMOPHTHALIDE;5-Bromo-1-isobenzofuranone;5-Bromophthalide99%MIN.;5-Bromophthalide,98%;5-bromo-3H-isobenzofuran-1-one

MF:  C8H5BrO2

NW: 213.03

Assay: ≥99%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage: FG-4592 is an HIF α prolyl hydroxylase inhibitor  in clinical development for the treatment of anemia.

Related Intermediates:

1) Methyl 4-Hydroxy-7-Phenoxyisoquinoline-3-Carboxylate 1455091-10-7

2) Methyl 4-Hydroxy-1-Methyl-7-Phenoxyisoquinoline-3-Carboxylate CAS 1421312-34-6

3)  5-Bromophthalide  CAS 64169-34-2