Home > Pharmaceutical Intermediates > Special Intermediates > 42288-26-6,N-(4-CYANO-PHENYL)-GLYCINE For Making Dabigatran

42288-26-6,N-(4-CYANO-PHENYL)-GLYCINE For Making Dabigatran

Payment Type:	L/C,T/T
Incoterm:	FOB
Min. Order:	1 Kilogram
Delivery Time:	15 Days

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Basic Info

Model No.: 42288-26-6

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: 100KG

Certificate: ISO

Product Description

The intermediate of dabigatran etexilate, N-(4-CYANO-PHENYL)-GLYCINE CAS number is 42288-26-6,appearance is off-white powder and it is the side chain of the N-3 intermediate of dabigatran etexilate. its preparation process is relatively simple as following: at room temperature, take p-aminobenzonitrile 11.8g, potassium carbonate 10.0g added to 100ml of acetonitrile, during stirring, drop ethyl bromoacetate 16.7g, warmed to reflux, after reacted for 16hours, cooled to room temperature, The mixture was filtered, concentrated to removed solvent, add water to stir the residue substance, filtered, washed twice with water and recrystallized from toluene to obtain 17.9 g of the target compound N-(4-CYANO-PHENYL)-GLYCINE CAS 42288-26-6. According to the market user feedback it can also be used for the synthesis of other compounds. At our company, N-(4-CYANO-PHENYL)-GLYCINE 42288-26-6 is the largest quantities intermediate in the production of dabigatran, and in general our stocks are kept above 2 tonnes.

Thera. Category: Antithrombotic/Blood thinners

Cas No.:42288-26-6

Synonym:N-(p-Cyanophenyl)glycine;Dabigatran pharMaceutical interMediate;Glycine, N-(4-cyanophenyl)-;Dabigatran Etexilate Intermediate 2; N-(4-CYANO-PHENYL)-GLYCINE;Dabigatran Intermediate 2;[(4-Cyanophenyl)aMino]acetic Acid;4-(((Carboxy)Methyl)aMino)benzonitrile;

42288-26-6

Molecular Weight:176.17202

Molecular formula:C9H8N2O2

Purity: ≥99.%

Appearance: White Crystalline solid

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage: It can treat and prevent blood clots, reducing the risk of stroke.

Related intermediate:

CAS	Chemical Name	Specification		Color
41263-74-5	4-(MethylaMino)-3-nitrobenzoic acid	HPLC	≥99.0%	pale brown
103041-38-9	N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER	HPLC	≥99.0%	off white to white
429659-01-8	ETHYL N-[4-(METHYLAMINO)-3-NITROBENZOYL]-N-PYRIDIN-2-YL-SS-ALANINATE	HPLC	≥99.0%	orange yellow solid
42288-26-6	N-(4-CYANO-PHENYL)-GLYCINE	HPLC	≥99.0%	off white
42288-26-6	N-(4-CYANO-PHENYL)-GLYCINE	Loss on drying	≤1.0%	off white
212322-56-0	3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-PROPIONIC ACID ETHYL ESTER	HPLC	≥99.0%	off white
		Melting point	101.0°C~106.0°C
		Single impurity	≤0.3%
		Loss on drying	≤0.5%
		Residue on ignition	≤0.5%
		Assay	≥98.0%
211915-84-3	Synonyms:3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester	HPLC	≥99.0%	off white
		Single impurity	≤0.3%
		Loss on drying	≤0.5%
		Residue on ignition	≤0.5%
		Assay	≥99.0%
872728-85-3	N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]arbonyl]-N-2-pyridinyl-beta-alanine ethyl ester 4-methylbenzenesulfonate	HPLC	≥97.0%	off white
211915-06-9	Dabigatran Etexilate	HPLC	≥98.0%	white
		Single impurity	≤0.2%
		Loss on drying	≤1.0%
		Assay	≥98.0%
872728-81-9	Dabigatran etexilate mesylate	HPLC	≥99.0%	light yellow solid
		Single impurity	≤0.5%
		Loss on drying	≤1.0%
		Residue on ignition	≤0.1%
		Heavy melta	≤20 ppm
		Assay	≥98.5%

Dabigatran Intermediate 2 CAS 42288 26 6 CAS 42288 26 6 CAS Number 42288 26 6

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