41051-15-4,Methyl 4-methoxyacetoacetate Used for Making Dolutegravir

Basic Info

Model No.: 41051-15-4

Additional Info

Packaging: As required

Productivity: 10KG/M

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Certificate: Technical Support

Product Description

Methyl 4-methoxyacetoacetate cas number 41051-15-4 which is a colorless transparent liquid with an aromatic odor. It is an important pharmaceutical intermediate compound. It is mainly used in the synthesis of the new anti-AIDS drug Dolutegravir. Dolutegravir is the FDA's priority review drug and is expected to reach $1.62 billion in sales by 2020. The drug is safer than the existing HIV integrase inhibitors, Raltegravir and Elvitegravir. As a starting material for the synthesis of Dolutegravir, The quality of methyl 4-methoxyacetoacetate 41051-15-4 has a great influence on the further synthesis of Dolutegravir. Therefore, the study on the synthesis of methyl 4-methoxyacetoacetate has certain significance.

We are professional suppliers of 41051-15-4, Methyl 4-methoxyacetoacetate Used for Making Dolutegravir manufacturers and suppliers in China. which is an intermediate of Dolutegravir.These high quality products are formulated by adopting quality methods and using well-tested ingredients that are procured from the certified vendors of the market. We offer these products in proper packaging of diverse quantity to meet assorted requirements of the clients.

Thera. Category:Anti-HIV

Cas No.:41051-15-4

Synonyms:4-methoxy-3-oxo-butanoicacimethylester;Butanoic acid, 4-methoxy-3-oxo-, methyl ester;Methyl methoxyacetoacetate;METHYL 4-METHOXYACETOACETATE;METHYL 4-METHOXYACETOXYACETATE;METHYL 4-METHOXY-3-OXO-BUTANOATE;4-METHOXYACETOACETIC ACID METHYL ESTER;methyl 4-methoxy-3-oxobutyrate

MF:C6H10O4

NW:146.14

Assay: ≥99%

Packing:Export worthy packing

Material Safety Data Sheet:Available on request

Usage: Intermediate of Dolutegravir

We are availabe for several Intermediates of Dolutegravir:

1) (4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido

[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide CAS 1206102-11-5

2) Dimethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate CAS NO.1246616-66-9

3) 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid

CAS NO. 1335210-23-5

4) Methyl-5-(2,4-difluorobenzylcarbamoyl)-1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2-carboxylate

CAS NO.1616340-68-1

5) (4R,12aS)-N-(2,4-Difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]

pyrido[1,2-a]pyrazine-9-carboxamide CAS NO.1335210-35-9

6) (R)-3-AMINO-1-BUTANOL CAS NO.61477-40-5

7) 1051375-16-6, Dolutegarvir

8)Methyl 4-methoxyacetoacetate CAS NO.41051-15-4