1228780-51-5,ABT-199 Inter (2-(4-chlorophenyl)-4,4-diMethylcyclohex-1-enyl)Methanol

Basic Info

Model No.: 1228780-51-5

Additional Info

Packaging: AS REQUIRED

Productivity: KGS

Brand: VOLSENCHEM

Transportation: Air

Place of Origin: CHINA

Supply Ability: TRUE MANUFACTURER

Product Description

ABT199 Intermediate 2 has the Molecular Formula C15H19ClO and Molecular Weight 250.76376 CAS NUMBER 1228780-51-5. ABT199 Intermediate 2 is obtained by reduction reaction of ABT199 intermediate 1. The synthesis of ABT199 intermediate 1 has been described in detail and we will not described here repeatedly. Now we introduce another method of synthesis of ABT199 Intermediate 2, Use METHYL 4,4-DIMETHYL-2-OXOCYCLOHEXANECARBOXYLATE as raw material add NaH and other solvent to obtain methyl 2-hydroxy-4,4-dimethylcyclohex-1-enecarboxylate, adding 4-chlorophenylboronic acid to obtain Methyl-4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro- [1,1'-biphenyl] -2-carboxylate, adding LiBH4, MeOH and the like to obtain the target intermediate ABT199 intermediate 2 cas 1228780-51-5. The above two synthetic methods described which is better, we do not make specific comments, because it needs to use accurate experimental data to illustrate.
Thera. Category: Leukemia Drugs

Cas No.: 1228780-51-5

Synonyms:2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexene-1-methanol; (2-(4-chlorophenyl)-4,4-diMethylcyclohex-1-enyl)Methanol;

Molecular Formula:C15H19ClO

Molecular Weight: 250.76376

Purity: ≥98%

Packing: Export worthy packing

Material Safety Data Sheet: Available on request